How To Use Nystatin Oral Suspension

What is Nystatin Oral Interruption and how is it used?

Nystatin Oral Interruption is a prescription medicine used to treat the symptoms of fungal infections and candidiasis (yeast infections). Nystatin Oral Break may be used alone or with other medications.

Nystatin Oral Suspension belongs to a class of drugs called Antifungals, Other; Antifungals, Systemic.

What are the possible side effects of Nystatin Oral Suspension?

Nystatin Oral Suspension may cause serious side effects including:

fast heart rate,
trouble breathing,
severe skin reaction,
fever,
sore throat,
swelling in your face or natural language,
burning in your optics, and
skin pain, followed by a red or purple pare rash that spreads (especially in the face or upper trunk) and causes baking and peeling

Get medical help right away, if you accept any of the symptoms listed above.

The about common side effects of Nystatin Oral Suspension include:

oral fissure irritation,
upset tum,
nausea,
airsickness,
diarrhea, and
skin rash

Tell the doctor if yous take whatever side effect that bothers you or that does not go abroad.

These are not all the possible side furnishings of Nystatin Oral Suspension. For more than information, enquire your doctor or pharmacist.

Phone call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Clarification

Nystatin is an antimycotic polyene antibiotic obtained from Streptomyces noursei. Structural formula:

NYSTATIN ORAL SUSPENSION Structural Formula Illustration

Nystatin Oral Suspension is a cherry-mint flavored suspension for oral administration. Information technology contains 100,000 USP Nystatin Units per mL. Inactive ingredients: alcohol ( ≤ 1% 5/five), carboxymethylcellulose sodium, season, glycerin, methylparaben, propylparaben, purified water, saccharin sodium, sodium citrate, and sucrose (fifty% w/v). May also contain citric acid for pH adjustment.

INDICATIONS

Nystatin Oral Suspension is indicated for the treatment of candidiasis in the oral crenel.

DOSAGE AND ADMINISTRATION

Infants: ii mL (200,000 units) four times daily (in infants and young children, use dropper to identify half of dose in each side of mouth and avoid feeding for five to 10 minutes). NOTE: Limited clinical studies in premature and low birth weight infants signal that 1 mL four times daily is effective.

Children and Adults: four–six mL (400,000 to 600,000 units) four times daily (half of dose in each side of mouth). The preparation should exist retained in the oral fissure as long as possible before swallowing.

Continue handling for at to the lowest degree 48 hours after perioral symptoms have disappeared and cultures demonstrate eradication of Candida albicans.

HOW SUPPLIED

Nystatin Oral Suspension, USP, 100,000 USP Nystatin Units per mL, is available every bit a cherry-mint flavored, light flossy yellow, set-to-use interruption in sixty mL bottles with calibrated dropper and 473 mL bottles.

Storage

Shop at xx°-25°C (68°-77°F) with excursions permitted between fifteen°-30°C (59°-86°F) [See USP Controlled Room Temperature]; avoid freezing.

Manufactured for: Qualitest Pharmaceuticals, Huntsville, AL 35811. Revised: Apr 2015

SLIDESHOW

Mouth Problems: TMJ, Herpes Sores, Painful Gums and More Run across Slideshow

Side Effects & Drug Interactions

SIDE Furnishings

Nystatin is well tolerated even with prolonged therapy. Oral irritation and sensitization take been reported (Run across PRECAUTIONS: Full general).

Gastrointestinal

Diarrhea (including ane instance of bloody diarrhea), nausea, vomiting, gastrointestinal upset/disturbances.

Dermatologic

Rash, including urticaria has been reported rarely. Stevens-Johnson syndrome has been reported very rarely.

Other

Tachycardia, bronchospasm, facial swelling, and nonspecific myalgia take also been reported.

DRUG INTERACTIONS

No information provided.

WARNINGS

No information provided.

PRECAUTIONS

General

This medication is not to be used for the handling of systemic mycoses.

Discontinue treatment if sensitization or irritation is reported during use.

Carcinogenesis, Mutagenesis, Impairment Of Fertility

No long-term animal studies take been performed to evaluate carcinogenic potential. At that place also have been no studies to determine mutagenicity or whether this medication affects fertility in males or females.

Pregnancy

Teratogenic Effects - Category C

Creature reproduction studies have non been conducted with nystatin oral interruption. Information technology is besides not known whether nystatin oral intermission can cause fetal harm when administered to a pregnant adult female or tin can bear upon reproduction capacity. Nystatin oral suspension should exist given to a pregnant woman merely if clearly needed.

Nursing Mothers

It is not known whether nystatin is excreted in human milk. Because many drugs are excreted in homo milk, circumspection should be exercised when nystatin is administered to a nursing woman.

Pediatric Use

See DOSAGE AND ADMINISTRATION.

Overdose & Contraindications

OVERDOSE

Oral doses of nystatin in excess of five million units daily take caused nausea and gastrointestinal upset.

At that place take been no reports of serious toxic furnishings or superinfections (See CLINICAL PHARMACOLOGY: Pharmacokinetics ).

CONTRAINDICATIONS

The preparation is contraindicated in patients with a history of hypersensitivity to any of its components.

CLINICAL PHARMACOLOGY

Pharmacokinetics

Gastrointestinal assimilation of nystatin is insignificant. Most orally administered nystatin is passed unchanged in the stool. In patients with renal insufficiency receiving oral therapy with conventional dosage forms, pregnant plasma concentrations of nystatin may occasionally occur.

Microbiology

Nystatin is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-similar fungi. Candida albicans demonstrates no meaning resistance to nystatin in vitro on repeated subculture in increasing levels of nystatin; other Candida species become quite resistant. Generally, resistance does not develop in vivo. Nystatin acts by bounden to sterols in the cell membrane of susceptible Candida species with a resultant alter in membrane permeability allowing leakage of intracellular components. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

PATIENT INFORMATION

No data provided. Delight refer to the PRECAUTIONS section.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.